Year: 1993 Source: Drugs, v.46, no.5, (November 1993), p.895-924 SIEC No: 19970062

The overall efficacy of fluvoxamine, 100 to 300 mg/day for 4-6 weeks, in once daily or divided dosages appears to be at least comparable to that of imipramine, and similar to that of clomipramine, dothiepin, mianserin, and moclobemide. Fluvoxamine may be particularly beneficial in: potentially suicidal patients with severe depression; in those with an underlying compulsive personality or cardiovascular disorder; in patients with coexistent anxiety or agitation; and in the elderly. (150 ref.)