Clinical Safety and Efficacy of Tianeptine in 1,858 Depressed Patients Treated in General Practice

1,858 depressed patients were analysed to evaluate the safety of tianeptine in the ambulatory treatment of depression. Only 1 patient completed suicide. At inclusion, 79% of the patients were considered to be extremely ill. By the end of the trial period, 66.5% of patients had shown improvement. With regard to the clinical tolerance of tianeptine, somatic complaints were rarely reported & adverse events necessitating premature termination of treatment were without clinical severity.