A Case of Monthly Unipolar Psychotic Depression With Suicide Attempt by Self-Burning: Selective Response to Bupropion Treatment

A second case of monthly, unipolar, psychotic depression is presented, involving a 26-year-old woman whose illness had a postpartum onset, recurred premenstrually for 33 consecutive months, & involved a suicide attempt by self-burning. Whereas various antidepressant, antipsychotic, & hormonal treatments were ineffective, bupropion (together with low-dose trifluoperazine) induced an immediate & complete remission that was maintained at a 16-month evaluation. (40 refs.)