Year: 1992 Source: The Lancet, v.339, no.8799, (April 18, 1992), p.1001-1002 SIEC No: 19920189

2 letters to the editor are included. Severs argues Engelberg’s assertion that increased rates of suicide in cholesterol-lowering trials results in alterations in mood because of a reduced expression of serotonin receptors in brain cell membranes. In the second letter, the authors suggest that the increased suicide rate may result not from cholesterol reduction, but because of drugs used. Their examination of several papers do not support a causal connection between low cholesterol & suicide.