Year: 1991 Source: Acta Psychiatrica Scandinavica, v.84, no.1, (July 1991), p.110-111 SIEC No: 19911491

The assymetry of tritiated imipramine binding sites, associated with serotonergic mechanisms, were investigated in the orbital frontal cortex in 12 subjects who died of natural causes & who did not have a history of mental disorders. Preliminary findings of gender differences of serotonergic mechanisms in some areas of the brain are in accordance with the observed gender differences in a variety of serotonin-regulated behaviours & mental disorders, including suicidal behaviours. (11 refs.)