Year: 1991 Source: Biological Psychiatry, v.29, no.10, (May 15, 1991), p.1016-1022 SIEC No: 19911299

Serotonin-sensitive imipramine binding was determined in the left & right hemisphere of frontal cortex of suicide victims & nonpsychiatric controls. The Kd was significantly higher in left than right hemisphere in normal controls. There were no differences in Bmax & Kd or Bmax between left & right hemispheres in normals & suicides. Results do not support the finding of hemispheric assymetry of 5-HT uptake as measured by imipramine binding (Bmax) in postmortem tissue from controls & suicides.