Studied 325 cases of deliberate self-poisoning admitted to the Princess Alexandra Hospital in Brisbane, 1985-86. Benzodiazepines were consumed the most often followed by antidepressant drugs. Almost 1/2 of the Ss had a previous history of self-poisoning. Comparison of these results with past surveys show that the profile of deliberate self-poisoning is changing. A review of the prescribing patterns of antidepressants for individuals at high-risk of self-poisoning is suggested. (15 refs.)