Year: 1991 Source: Journal of the American Academy of Child & Adolescent Psychiatry, v.30, no.2, (March 1991), p.179-86 SIEC No: 19910643

This study analyzed the effect of fluoxetine treatment for obsessive-compulsive disorder among 6 patients, 10 to 17 years old. The authors found that self-injurious ideation or behavior appeared or intensified during the treatment. 3 hypotheses are discussed: coincidence; medication-induced agitation, disorganization, or mood changes; or, a specific serotonergic-mediated effect on the regulation of aggression. (VM)