“Suicidal Preoccupation During Fluoxetine Treatment”: Dr. Teicher and Associates Reply

Responds to the comments by Papp & Gorman (see PA Vol 78:4736) on Teichers’ earlier report on suicidal preoccupation during fluoxetine treatment (see PA Vol 77:18011). Teicher et al find Papp & Gorman’s hypothesis that these suicidal obsessions may be part of a specific serotonin reaction resulting from a sudden increase in serotonin neurotransmission, interesting & important. However, they are cautious about accepting this hypothesis until more direct neuropharmacologic data are available.