Year: 1990 Source: Archives of General Psychiatry, v.47, no. 11, (November 1990), p.1038-1047 SIEC No: 19901973

This study attempts to discover which brain regions are involved with serotonin (5-HT-2) deficiencies in those who display suicidal behaviour. The authors determined the pattern of 5-HT-2 receptor binding sites in prefrontal cortex compared with temporal cortex in 11 suicide victims & 11 matched controls. They also examined B-adrenergic receptor binding sites. Binding to 5-HT-2 & B-adrenergic sites in slide-mounted sections correlated strongly with binding site number in membrane preparations.VM