Year: 1990 Source: Annals of Emergency Medicine, v.19, no.4, (April 1990), p.378-381 SIEC No: 19900893

The case of a 17 yr old girl who ingested 24-36 g fenoprofen as a suicidal gesture is presented. She presented with coma, hypotension, metabolic acidosis & respiratory depression within 4 hours of ingestion. The propionic acid derivatives of nonsteroidal anti-inflammatory drugs, including fenoprofen & ibuprofen, are rarely associated with severe toxic effects. This is the first report of pure fenoprofen overdose presenting as coma and metabolic acidosis.