Year: 1988 Source: Acta Psychiatrica Scandinavica, v.78, no.5, (November 1988). p.529-535 SIEC No: 19890684

The authors review the accumulating evidence from preclinical, clinical & postmortem studies suggesting that abnormality in serotonin systems may be associated with both attempts at suicide & aggression towards others & inanimate objects. Although these behaviors are multidetermined they often involve poor impulse control, which may reflect low central serotonin turnover. The need for further studies of possible peripheral biological markers for suicical & impulsive behavior is discussed.