Year: 1988 Source: Neurobiology of Aging, v.9, no.1, (January-February 1988), p.101-117 SIEC No: 19890010

This review examines various research approaches undertaken to investigate possible central nervous system correlates of major depressive disorder & relates findings from these studies to alterations in central nervous system & neuroendocrine function that normally accompany aging in humans. Topics include: epidemiology of depression & suicide in the elderly; monamine theories of depression; neuroendocrine disturbances in depression; imaging studies. (KM)