Suicide risk was investigated in a 1970-1981 study of psychiatric patients with primary unipolar depression (N=705), secondary unipolar disorder (N=302), & bipolar affective disorder(N=586). Suicide rates among the study subjects were compared with the general population of Iowa. Increased risk was found in all pychiatric groups except female patients with BAD. 30 suicides occurred during the first 2 years of follow-up. Highest rates were for male BAD and female primary unipolar depression.