The Thyrotropin Response to Thyrotropin-Releasing Hormone as a Biological Marker of Suicidal Risk in Depressive Patients
Korner A~~Kirkegaard C~~Larsen J K
Followed 306 depressed patients for a mean of 5.8 (SD 2.9) yrs. The thyrotropin-stimulating hormone (TSH) response to thyrotropin-releasing hormone (TRH) stimulation in the 18 patients who committed suicide was lower than in the patients who did not commit suicide. The difference is not statistically significant. It is concluded that the TSH response to TRH cannot be said to identify the patients who later commit suicide.