The successful management of a case of quinine overdose with blindness is described. Treatment of moderate poisoning with ingestion of less than 10g of quinine should consist of immediate & thorough gastric lavage, forced acid diuresis, immediate bilateral stellate ganglion blockage repeated if there is clinical improvement in vision. With a larger overdose or when coma or convulsions occur, haemodialysis, peritoneal dialysis or preferably haemoperfusion should be considered. 15 Refs. (LH)