Year: 1986 Source: Canadian Journal of Psychiatry, v.21, no.8, (November 1986), p.757-758 SIEC No: 19861555

The authors describe the first case report in the psychiatric literature of death from an overdose of amantadine hydrochloride (Symmetrel). Amantadine, an antiviral agent, is used to treat neuroleptic induced extrapyramidal side effects. The pharmacology, adverse reactions and risks of using amantadine are briefly reviewed. (15 refs.)