Year: 1986 Source: American Journal of Psychiatry, v.143, no.4, (April 1986), p.519-522 SIEC No: 19861536

In a double bind crossover trial, carbamazepine, an anticonvulsant with primary effects on subcortical limbic structures,decreased the severity of behavioral dyscontrol in 11 women with borderline personality disorder significantly more than placebo. The authors emphasize the preliminary nature of their findings and discuss alternative hypotheses regarding mechanisms by which carbamazepine might influence behavioral dyscontrol.