The authors reviewed the charts of 160 patients discharged in 1981 from the 4 hospitals in Lansing, Michigan with a diagnosis of overdose. Females predominated (65%) & the median age was 27 years. The most common reason for intentional self-poisoning was “significant other” conflict (54.5%), followed by family conflict & financial problems. Benzodiazepines were most commonly used followed by acetylsalicylic acid & ethanol.