Year: 1983 Source: Psychiatry Research, v.9, (1983), p.179-189 SIEC No: 19850627

The purine metabolites hypoxanthine & xanthine were ananlysed in the CSF of 70 patients with depressive disorders & a control group of 26 nonpsychiatric individuals. Results indicated that raw CSF levels in depressed individuals were correlated with sex, age, height & weight. Hypoxanthine & xanthine appear to be linked with the expression of depressive symptomatology. Other significant findings related to depression, anger, suicidal tendencies, memory disturbance & lack of appetite are discussed