A study of 600 confirmed suicidal attempts by poisoning in New York City during 1960-61 reveals that the incidence of suicide attempts varies with age. Attempts at suicide by poisoning in adolescents are higher than those reported among adults. 75% of attempts by poisoning were made by females. 22% of the reported total were Puerto Ricans. 5 of the 600 attempts were successful. Suicidal threats or attempts should be taken seriously & the individuals referred for investigation & treatment.