Year: 2021 Source: Journal of Psychiatric and Mental Health Nursing. (2021). Published online 8 February 2021. https://doi.org/10.1111/jpm.12739; 00: 1– 10. https://doi.org/10.1111/jpm.12739 SIEC No: 20210332

Introduction
Meaning in life can be good protective factor against depression, hopelessness and suicidal ideation.
Aim
To analyse the mediating effect of meaning in life on the associations among hopelessness, depression and suicidal ideation.
Method
A cross‐sectional study was conducted among 90 patients diagnosed with depression. A structural equation modelling approach was applied for this path analysis to examine the mediating effect of meaning in life on the association among hopelessness, depression and suicidal ideation.
Results
The results showed that meaning in life mediated the association between hopelessness and depression. Hopelessness had a direct positive association with depression (β = 0.23, p < .03), and meaning in life had a direct negative association with depression (β = −0.51, p < .01) and indirect association with suicidal ideation through depression; this indirect association was −0.21 (p < .01).
Discussion
Meaning in life revealed strong mediating association with the relationship between hopelessness and depression. By reducing the level of depression, meaning in life demonstrated its mediator association with suicidal ideation.
Implications for Practice
Logotherapy is a meaning‐centred therapy to find meaning in life. Mental health nurses could help patients to manage their depression through logotherapy, thus leading to reductions in suicidal ideation.