Urban-rural differences in suicide in the state of Maryland: The role of firearms.

OBJECTIVES: To assess whether the use of firearms explains rural-urban differences in suicide rates. METHODS: We performed a retrospective analysis on all 6196 well-characterized adult suicides in Maryland from 2003 through 2015. We computed rate ratios by using census data and then stratified by sex, with adjustment for age and race. RESULTS: Suicide rates were […]

Hopelessness, Depression, Substance Disorder, and Suicidality: a 13-Year Community-Based Study

Using a longitudinal study design with a community sample of more than 3,000 participants, the authors examined if hopelessness was a long-term predictor of suicidal behaviours. The association of hopelessness at baseline & incident suicidal behaviours in the 13-year follow-up was assessed, adjusting for depression & substance use disorders. Hopelessness was predictive of suicide, suicide […]

Increased Risk of Suicidal Ideation in Smokers and Former Smokers Compared to Never Smokers: Evidence From the Baltimore ECA Follow-Up Study

In this study, the age-adjusted incidence of suicide ideation was highest among current smokers, followed by former, then never smokers. The adjusted hazard for suicide ideation was 2.22 & 1.19 for current & former smokers, respectively, compared to never smokers. Results indicate that current smokers have increased risks of suicide ideation above & beyond the […]

Posttraumatic Stress Disorder and Suicide Attempts in a Community Sample of Urban American Young Adults


Brain Region Specific Alterations in the Protein and mRNA Levels of Protein Kinase A Subunits in the Post-Mortem Brain of Teenage Suicide Victims

The objective of this study was to examine if changes in protein kinase A activity or in the protein & messenger RNA expression of any of its subunits are related to the pathophysiology of teenage suicide. The sample included 17 suicide victims & 17 nonpsychiatric control subjects. Protein kinase A activity was significantly decreased in […]

Anxiety Disorders and Risk for Suicide Attempts: Findings From the Baltimore Epidemiologic Catchment Area Follow-Up Study

This study sought to determine if the presence of an anxiety disorder was a risk factor for future suicide attempts. Data were drawn from the 13-year follow-up Baltimore Epidemiological Catchment Area survey. The presence of one or more anxiety disorders at baseline was significantly associated with subsequent onset suicide attempts after controlling for sociodemographic variables […]

Suicidal Ideation Among African-American Non-Injection Drug Users

This study explored correlates of suicide ideation among African Americans in a community-based cohort in Baltimore, Maryland. Participants had begun to use heroin, crack, or cocaine by means other than injection in the prior 10 years. An interview-administered questionnaire was used. Multiple logistic regression was used to identify factors independently associated with suicide ideation. The […]

Asthma, Suicidal Ideation, and Suicide Attempts: Findings From the Baltimore Epidemiologic Catchment Area Dollow-Up


Suicide Brain is Associated With Decreased Expression of Neurotrophins


Prevalence and Correlates of Suicidal Ideation Among Young Injection vs. Noninjection Drug Users


Differential and Brain Region-Specific Regulation of Rap-1 and Epac in Depressed Suicide Vicitms

Context  Depression is a major public health problem. Despite many years of research, the molecular mechanisms associated with depression remain unclear. Rap-1, activated in response to many extracellular stimuli, is one of the major substrates of protein kinase A, which participates in myriad physiologic functions in the brain, including cell survival and synaptic plasticity. Rap-1 […]

Abnormal Expression and Functional Characteristics of Cyclic Adenosine Monophosphate Response Element Binding Protein in Postmortem Brain of Suicide Subjects

Background  Cyclic adenosine monophosphate response element binding protein (CREB) is a transcription factor that, on phosphorylation by protein kinases, is activated, and in response, regulates the transcription of many neuronally expressed genes. In view of the recent observations that catalytic properties and/or expression of many kinases that mediate their physiological responses through the activation of […]

Church Attendance and Health


Suicide Risk and Mental Health Indicators: do They Differ by Abuse and HIV Status?


Firearm-Related Injury Surveillance in Maryland

The authors evaluated the system of firearm-related injury surveillance extant in Maryland to evaluate its ability to ascertain cases in the absence of a standard for the true number of cases. They found that the system was highly sensitive & had a very high positive predictive value. (4 refs)

African American Children’s Reports of Depressed Mood, Hopelessness, and Suicidal Ideation and Later Suicide Attempts


Achieving and Sustaining Statewide Collaboration for Suicide Prevention: the Maryland Youth Crisis Hotline Committee

Published in “Back to the Future: Refocusing the Image of Suicide,” ed. by J L McIntosh

School Team Model of Suicide Postvention

Group Crisis Intervention in a School Setting Following an Attempted Suicide

This paper reviews the phenomenon of adolescent suicide & offers a case study on the use of rapid & efficient group crisis intervention, referred to as a Crisis Management Briefing, directed towards the vicarious victims of an adolescent suicide attempt. (10 refs)

Longitudinal Predictors of Suicidal Behaviors

This document summarizes a study that identified psychiatric risk factors of suicide ideation, attempted suicide, & completed suicide in a longitudinal, community-based setting using data from the Baltimore Epidemiologic Catchment Area Program.

Altered Gene Expression of Brain-Derived Neurotrophic Factor and Receptor Tyrosine Kinase B in Postmortem Brain of Suicide Subjects

The present study was performed to examine whether the expression of brain-derived neurotrophic factor (BDNF) &/or activating receptor tyrosine kinase B (trk B) isoforms was altered in postmortem brain in subjects who complete suicide & whether these alterations were associated with specific psychopathologic conditions. Message RNA levels of BDNF & trk B were significantly reduced […]

Protein Kinase A in Postmortem Brain of Depressed Suicide Victims: Altered Expression of Specific Regulatory and Catalytic Subunits


Predicting Suicidal Risk in Schizophrenic and Schizoaffective Patients in a Prospective Two-Year Trial