Resource Tag: TWINS

Purpose: The aim of this study was to investigate if sickness absence and disability pension (SA/DP) in general and due to specific common mental disorders (CMDs) are associated with subsequent suicide attempt among women and men by taking familial factors (genetics and shared environment) into consideration. Methods: This register-based cohort study includes 4871 twin pairs 18-65 years […]

It has been well established that suicidal behavior is familial. Twin studies provide a unique opportunity to distinguish genetic effects from other familial influences. Consistent with findings from previous twin studies, including case series and selected samples, data from the population-based Swedish Twin Registry clearly demonstrate the importance of genetic influences on suicide. Twin studies […]

The purpose of the present study was to examine the relative association of genetic and environmental factors with individual differences in each of the proximal, jointly necessary, and sufficient causes for suicidal behavior, according to the Interpersonal-Psychological Theory of Suicide (IPTS; Joiner, 2005). We examined data on derived scales measuring acquired capability, belongingness, and burdensomeness (the […]

Objective Childhood adverse experiences are known to engender persistent changes in stress-related systems and brain structures involved in mood, cognition, and behavior in animal models. Uncertainty remains about the causal effect of early stressful experiences on physiological response to stress in human beings, as the impact of these experiences has rarely been investigated while controlling […]

The frequency of suicide-related behaviours was compared in twins from 2 survivor groups: those whose co-twin’s deaths were suicides (47 monozygotic & 31 dizygotic) & those whose co-twin’s deaths were nonsuicides (347 monozygotic & 170 dizygotic). The frequency of suicide attempts among suicide survivors was significantly higher in monozygotic than dizygotic twins, while the frequency […]

Evidence is mounting that genetic factors may be included in the many determinants of suicide. Clinical studies of psychiatric patients have suggested that risk of suicidal behaviour is increased by the presence of family history of suicidality, a claim that is also supported by findings of twin & adoption studies. In addition, molecular genetic studies […]

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Using adolescent twin data in the National Longitudinal Study of Adolescent Health, concordance in suicide ideation & attempts among monozygotic & dizygotic twins was examined. Heritability of risk factors for suicidal behaviours also was examined using Pearson correlation & mixed-model analyses. A trend of higher concordance in ideation & attempts was found among monozygotic than […]

Doubt remains as to whether the increased risk of suicide in monozygotic twins is a response to the intense grief over the loss of a close relative, or whether a common genotype is associated with suicidal behaviour. A number of researchers have reported greater suicide ideation among bereaved monozygotic twins as compared to dyzygotic twins, […]

This article reports on a door-to-door survey used to create a population-based twin register in Sri Lanka. The goal of this survey was to identify twins older than 18 years. A similar methodology was also used to identify a nontwin sample in order to determinate the degree to which twins were representative of the wider […]

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Published in “The Suicidal Process: Challenges for Treatment and Prevention”

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Published in “The Suicidal Process: Challenges for Treatment and Prevention”

Research studies on suicidal behavior among twins are reviewed. It is found that no methodologically sound study on twins reared apart has yet appeared, & so firm conclusions cannot be drawn from the research. Monozygotic twins reared together were found to have higher concordance rates for suicide than dizygotic twins reared together. Confounding factors are […]

The authors summarize a study that investigated the TPH-polymorphism in surviving monozygotic twins, whose twin siblings had committed suicide.

This article reviews the data supporting the role of genetic factors in the predisposition to suicidal behaviour & examines whether or not these factors are part of the genetic liability to mood disorders. The author finds that there is consistent evidence suggesting that genetic factors play an important role in the predisposition to suicide & […]

This study investigated demographic variables, including affected sibling pair status, as risk factors for suicidal behavior in schizophrenia patients of African descent. Demographic predictors of suicide included sib ship status & age of onset of illness. On further analysis of suicide in siblings, only a minority of sibling pairs was found to be concordant for […]