Association between buprenorphine for opioid use disorder and mortality risk

Veterans with opioid use disorder have an increased risk of suicide and overdose compared with the general population. Buprenorphine, a U.S. Food and Drug Administration–approved medication to treat opioid use disorder, has shown benefits, including decreased risk of illicit drug use and overdose. This study assesses the mortality outcomes with buprenorphine pharmacotherapy among[…]

Using mindfulness‑based cognitive therapy to prevent suicide among high suicide–risk patients who also misuse opioids: A preliminary probe of feasibility and effectiveness

Knowledge of how to effectively prevent suicide attempt (SA) in high suicide–risk patients who also misuse opioids is limited. In a subset of data from 36 participants with baseline opioid misuse in a randomized clinical trial testing adjunctive mindfulness-based cognitive therapy to prevent suicide among high suicide–risk veterans (n = 18 per treatment condition), MBCT-S reduced the[…]

Profiles of patients with opioid use disorders presenting a history of suicidal ideations and attempts

Suicide rates are higher for people with an opioid use disorder, compared to the general population. This study aims to characterize opioid agonist treatment entrants who present a history of suicidal ideations or suicide attempts, according to concurrent comorbidity profiles, in an opioid use disorder treatment facility. A chart review design was used. Data was[…]

National trends in suicide thoughts and behavior among US adults with opioid use disorder from 2015 to 2020

Suicide thoughts and behavior (STB) are associated with premature mortality and is disproportionately represented among those with opioid use disorder (OUD). Recent trends in STB among those with OUD are lacking. We investigated trends in STB among US adults with versus without OUD using six waves of cross-sectional, nationally-representative, epidemiological data.

Suicidal motivations reported by opioid overdose survivors: A cross-sectional study of adults with opioid use disorder

Background: Prior studies in heroin use disorder reported low rates (10%) of suicidal intention with non-fatal opioid overdose but did not assess dimensional ratings of suicidal ideation. This study aims to quantify the frequency and intensity of ratings of desire to die and perceived overdose risk proximal to the most recent opioid overdose event among individuals[…]

Suicide by opioid: Exploring the intentionality of the act

Opioid toxicity can result in life-threatening respiratory depression. Opioid-overdose mortality in the United States is high and increasing, but it is difficult to determine what proportion of those deaths might actually be suicides. The exact number of Americans who died of an opioid overdose but whose deaths might be classified as suicide remains unknown. It is important[…]

Housing First combined with Suicide Treatment Education and Prevention (HOME + STEP): Study protocol for a randomized controlled trial

Youth experiencing homelessness are at high risk for suicide, yet few studies have evaluated risk reduction interventions targeting suicidal ideation in this vulnerable population. A comprehensive approach to risk-reduction is needed that addresses basic needs and provides targeted interventions for those at highest risk. The protocol described builds on the design of the[…]

Characteristics of suicides and toxicology in a cohort of individuals with opioid use disorder

Suicide in patients with opioid use disorder (OUD) is a complex issue. In addition to accidental intoxications, a higher prevalence of fatal suicides in patients with OUD can be found compared to the general population. In this study, suicides with a diagnosis of OUD documented in the project “Suicides, A National Survey” were extracted from[…]

Healing the whole human being: Realist review of best practices and contextual factors for preventing & treating opioid misuse in Indigenous contexts in Alberta

Key Messages
• Colonization and resulting traumas directly impact addictions & mental health among Indigenous people, perpetuating stigma, misinformation & mistrust around accessing addictions services
• Improving coordination between all levels of healthcare (e.g., primary/tertiary) and service domains (e.g., residential treatment, incarceration to community & vice versa) is key to sustained treatment outcomes

Association of opioids prescribed to family members with opioid overdose among adolescents and young adults

Importance  Family members are cited as a common source of prescription opioids used for nonmedical reasons. However, the overdose risk associated with exposure to opioids prescribed to family members among adolescents and young adults is not well established. Objective  To assess the association of opioids prescribed to family members with pharmaceutical opioid overdose among youth. Design, Setting,[…]