Association of Suicide Attempts With Acne and Treatment With Isotretinoin: Retrospective Swedish Cohort Study

The risk of attempted suicide before, during, & after treatment with isotretinoin for severe acne was analyzed in a retrospective cohort study of 5,756 Swedish patients, aged 15-49 years. Standardised incident ratios were calculated up to 3 years before, during, & up to 15 years after the end of treatment. 128 patients were admitted to […]

Overview of Existing Research and Information Linking Isotretinoin (Accutane), Depression, Psychosis, and Suicide

Reports of intracranial hypertension, depression, & suicide ideation with Accutane use have prompted an examination of its serious & life-threatening potential. Although the manufacturer has added a warning to the product label, this drug is overprescribed for all forms of acne, including mild & moderate cases that have not been treated with alternative medications with […]

Isotretinoin, Depression and Suicide Ideation in an Adolescent Boy

This letter to the editor presents the case of a 16-year-old male who experienced two depressive episodes which were strongly associated with isotretinoin treatment. The severity of symptoms, including suicide ideation, required closed ward care. The patient made a complete recovery after the initiation of antidepressant drug therapy. (3 refs.)

Patients’ Perceptions of Isotretinoin, Depression and Suicide

Suicide, Depression, and Isotretinoin: is There a Casual Link?

An Analysis of Reports of Depression and Suicide in Patients Treated With Isotretinoin

Isotretinoin, Depression and Suicide: a Review of the Evidence