Regional clozapine, ECT and lithium usage inversely associated with excess suicide rates in male adolescents

Advanced psychiatric treatments remain uncertain in preventing suicide among adolescents. Across the 21 Swedish regions, using nationwide registers between 2016–2020, we found negative correlation between adolescent excess suicide mortality (AESM) and regional frequencies of clozapine, ECT, and lithium (CEL) usage among adolescents (β = −0.613, p = 0.0003, 95% CI: −0.338, −0.889) and males (β = −0.404, p = 0.009, 95% CI: −0.130, −0.678). No […]

Risk factors for suicide among patients having received treatment with electroconvulsive therapy: A nationwide study of 11,780 patients

Objectives Despite the putative anti-suicidal effect of electroconvulsive therapy (ECT), patients receiving ECT remain at high risk of dying from suicide due to the severity of their underlying mental illness. We aimed to quantify this risk and to identify risk factors for suicide among patients receiving ECT. Methods Using nationwide Danish registers, we identified all […]

Electroconvulsive therapy and the risk of suicide in hospitalized patients with major depressive disorder

Importance  Electroconvulsive therapy (ECT) is indicated for severe depression, including depression with psychosis, catatonia, and/or an elevated suicide risk. However, the association of ECT with suicide risk is uncertain. Objective  To determine the association between ECT and the risk of suicide in patients with unipolar major depressive disorder. Design, Setting, and Participants  This registry-based cohort study used patient […]

Magnetic seizure therapy for suicidality in treatment-resistant depression

Importance  There is an unmet need for effective treatments for suicidality in mental disorders. Magnetic seizure therapy (MST) has been investigated as an alternative to electroconvulsive therapy, a known effective treatment for suicidality, in the management of treatment-resistant major depressive disorder, with promising findings. Yet, there are very limited data on the association of MST with […]

Electroconvulsive therapy in patients with skull defects or metallic implants: A review of the literature and case report.

ECT is an effective and safe alternative in patients with a history of brain trauma and metallic plate implantation who subsequently develop treatment-resistant depression and associated suicidal ideas or plans refractory to management with medications.

Depression in Adolescents: Current Treatments, Suicidality and Evaluation of Novel Treatment Strategies

Depression in the child & adolescent population has been an area of research for over 20 years. Among novel therapeutic strategies, transcranial magnetic stimulation has demonstrated the most favourable side effect profile. Until this time, there are no published suicide attempts associated with this treatment & it may offer an option that is not associated […]

Suicide Risk and Psychopharmacology: Assessment and Management of Acute and Chronic Risk Factors

Although suicide is a rare & difficult-to-predict event, psychiatrists can make an important impact on patient mortality by identifying & reducing both acute & chronic risk factors for completed suicide. This article first discusses acute risk factors & treatment for same & then discusses chronic risk factors & treatment. (20 refs.)

All-Cause Mortality Among Recipients of Electroconvulsive Therapy: Register-Based Cohort Study

The risk of mortality was assessed among recipients of electroconvulsive therapy compared with other psychiatric inpatients in Denmark over a 25-year period, 1976-2000. There were 783 deceased inpatients who had received electroconvulsive therapy compared with 5781 who had not. Patients who had received electroconvulsive therapy had a lower overall mortality rate from natural causes but […]

Managing Suicidality in Schizophrenia

OBJECTIVE: The primary objective of this review article is to provide a coherent, systematic synthesis of the literature on the management of suicidality in schizophrenia that is relevant to the front-line clinician. METHOD: Literature searches were conducted on MEDLINE (1996 to 2007) and PubMed (1993 to 2007), using the key words “schizophrenia” and “suicide,” as […]

Treating Suicidality in Depressive Illness. Part 2: Does Treatment Cure or Cause Suicidality?

Objectives: To systematically review studies of treatment efficacy for suicidality in mood disorders. To consider the evidence for whether antidepressants may induce suicidality. Method: Systematic review of the literature. Results and Conclusions: There is fairly good evidence that lithium reduces completed suicide and attempt rates in people with bipolar disorder and recurrent unipolar depression. Antidepressants […]

Psychopharmacologic Management of Suicidality in Personality Disorders

To review the evidence for the efficacy of pharmacotherapy and other biological treatments in suicidality associated with personality disorders, chiefly borderline personality disorder. Systematic review of the literature. Studies evaluating treatment of suicidality in personality disorders are absent. However, several studies examine the efficacy of pharmacotherapy for core symptom clusters that are closely associated with […]

Relief Expressed Suicidal Intent by ECT: a Consortium for Research in ECT Study


Suicidal Behaviour in Bipolar Disorder: Risk and Prevention

Prevention of Suicide in the Elderly

The use of Electroconvulsive Therapy and the Length of Stay of Psychiatric Inpatients at King Chulalongkorn Memorial Hospital, Thai red Cross Society


Suicide in Bipolar Disorder: Risks and Management


Preventing Suicide in Older People

Suicide and ECT

Please see SIEC #1983-0433 for the article by Watkins et al.

ECT for Psychotic Depression Associated With a Brain Tumor

This letter to the editor presents the case of a woman with treatment-resistant depression & suicidal ideation associated with a recurrent brain tumor, who experienced rapid remission of her symptoms after ECT. (2 refs)

The Effect of Electroconvulsive Therapy on Suicide Risk in Patients With Mood Disorders

The authors discuss the effect of electroconvulsive therapy (ECT) on suicide risk in patients with mood disorders, using a review of the available data on the short-term & long-term effects of ECT on suicide mortality among patients with mood disorders. They conclude that ECT has an acute but not a long-term beneficial effect on suicidality. […]

Evaluation and Management of Geriatric Depression in Primary Care


Inadequate Treatment for Major Depression Both Before and After Attempted Suicide

Published in “The Suicidal Process: Challenges for Treatment and Prevention”

Do Psychosocial and Pharmacological Interventions Reduce Suicide in Schizophrenia and Schizophrenia Spectrum Disorders?

This article reviews findings regarding the particular nature of suicidal behaivours among patients with comorbid conditions & across the diverse spectrum of disorders that categorize schizophrenia. The author provides a brief epidemiological consideration of suicide in schizophrenia & reviews risk factors for suicide among this sub-population. Shortcomings of previous research & possible avenues for future […]