Association of gender-affirming hormone therapy with depression, thoughts of suicide, and attempted suicide among transgender and nonbinary youth

Purpose: There are no large-scale studies examining mental health among transgender and nonbinary youth who receive gender-affirming hormone therapy (GAHT). The purpose of this study is to examine associations among access to GAHT with depression, thoughts of suicide, and attempted suicide among a large sample of transgender and nonbinary youth. Methods: Data were collected as […]

Mental disorders and subsequent suicide events in a representative sample.

Objective : This study examined the patterns of association between mental disorders and subsequent suicide in a community sample representative of the Canadian household population. Methods : This retrospective cohort study used data from the Canadian Community Health Survey 2002 linked to the Death Database 2000-2011 and the Hospitalization Database 1999/2000-2012/2013) (n=27,000). Mental disorders (past year […]

Gender-specific factors related to suicidal ideation among community-dwelling stroke survivors: The 2013 Korean health survey.

We assessed gender-specific factors associated with suicidal ideation among communitydwelling stroke survivors. In total, 4,322 stroke survivors who participated in the 2013 Korean Community Health Survey were included in the final analysis. Sociodemographic information, socio-family relationships, health behaviors, health status, and suicidal ideation were assessed using a standardized questionnaire. On fully adjusted analysis, suicidal ideation […]

Social-cognitive and social-behavioral correlates of suicide risk in college students: Contributions from interpersonal theories of suicide and depression.

Joiner’s interpersonal-psychological theory of suicide (IPTS) is predated by literature examining maladaptive interpersonal behaviors associated with depression; however, research has not examined the potential relevance of such behaviors for the IPTS. The current study aimed to expand understanding of suicide risk by examining two maladaptive interpersonal behaviors in the context of Joiner’s IPTS model. Structural […]

Understanding depression and thoughts of self-harm in autism: A potential mechanism involving loneliness.

Background: Individuals with Autism Spectrum Disorder (ASD) are at increased risk of suicidal ideation and behavior. This study characterized the inter-relationships between loneliness, depression and thoughts of self-harm in adults with ASD. Method: Participants were 71 adults with ASD who completed questionnaires that provided information on loneliness, depression and thoughts of self-harm. Relationships between study […]

Reduced left precentral regional responses in patients with major depressive disorder and history of suicide attempts.

Every year, one million individuals world over die from suicide [1]. This is a serious global health problem, but suicide is difficult to predict and prevent in majority of the people at risk. Although the pathogenesis of suicide is multifactorial, the strongest predictor of risk for a future attempt is a history of suicidal behavior […]

Resting vagal tone is negatively associated with suicide ideation.

  The present study aimed at investigating whether resting vagally mediated heart rate variability (HRV) as a trait-like biomarker of cognitive inhibitory control capacity is related to suicide ideation in a sample without suicide attempt history. The relation between resting vagally mediated HRV and suicide ideation may be interpreted as indicating that reduced inhibitory cognitive […]

Suicides during pregnancy and 1 year postpartum in Sweden, 1980-2007.

Although the incidence of suicide among women who have given birth during the past 12 months is lower than that of women who have not given birth, suicide remains one of the most common causes of death during the year following delivery in high-income countries, such as Sweden. The maternal suicide ratio was 3.7 per […]

Differential neural processing of social exclusion in adolescents with non-suicidal self-injury: An fMRI study.

Non-suicidal self-injury (NSSI) is highly prevalent in adolescence and has been suggested as an autonomous diagnosis in the Diagnostic and Statistical Manual (DSM-5). Social rejection is as potential risk-factor for NSSI and depression in adolescence. Objectives of this study were to identify differences in neural processing of social rejection in depressed adolescents with and without […]

Case report of body dysmorphic disorder in a suicidal patient.

Few reports exist about the treatment of body dysmorphic disorder (BDD) in patients who are suicidal. This case report describes a 19-year-old male with BDD who had delusional-intensity beliefs about facial disfigurement that had gradually intensified over a 2-year period. However, he was initially misdiagnosed with depression partly because he was admitted immediately after a suicide […]

Synergistic effects of lifetime psychiatric disorders on suicidal ideation among blacks in the USA.

In this study, we aimed to investigate the synergistic effects of lifetime psychiatric disorders including general anxiety disorder (GAD), major depressive disorder (MDD), and drug abuse disorder (DAD) on serious suicidal thoughts among a nationally representative sample of Blacks in the USA. Individuals with comorbid GAD and MDD [odds ratio (OR) = 3.61, 95 % confidence interval […]

Cognitive inhibition in depression and suicidal behavior: A neuroimaging study.


Sensation seeking as a potential screening tool for suicidality in adolescence.

Although suicide could be an adverse health problem related to sensation seeking, this relationship has not been rigorously evaluated. The purpose of this study was to evaluate the relationship between sensation seeking and suicidality (suicidal ideation and plan) among adolescents and to test the influence of depressive symptom on this relationship. Sensation seeking can contribute […]

Depression: Understanding the black dog.

Having suffered from major depression for much of her life, Stephanie Sorrell has learned to work with the disease rather than against it. Where so many mental-health books feature Ôfighting and overcomingÔ depression, her experience and understanding have enabled her to see the value of the condition rather than what it can take away. In […]

Validation of the Edinburgh postnatal depression scale(EPDS)for screening of major depressive episode among adults from the general population.

Standardized questionnaires designed for the identification of depression are useful for monitoring individual as well as population mental health. The Edinburgh Postnatal Depression Scale (EPDS) has originally been developed to assist primary care health professionals to detect postnatal depression, but several authors recommend its use outside of the postpartum period. In Brazil, the use of […]

Association between serum cholesterol and depression, aggression and suicidal ideation in war veterans with posttraumatic stress disorder: A cross-sectional study.


Back from the brink: True stories & practical help for overcoming depression & bipolar disorder.

On July 24th, 2004, author Graeme Cowan took pen to paper and said goodbye to his family. “I just can’t be a burden any longer,” he wrote. After four failed suicide attempts, and a five-year episode of depression that his psychiatrist described as the worst he had ever treated, Cowan set out on a difficult […]

Living with a black dog: His name is depression.

Living with a Black Dog is perhaps the most useful book ever created about depression. In simple text and strongly supportive illustrations, this slim volume examines, explains, and demystifies one of the most widespread and debilitating problems afflicting modern society(from review).

Correlates of Depressed Mood among Young Stimulant-Using Homeless Gay and Bisexual Men.

Homeless gay and bisexual (G/B) men are at risk for suicide attempts and have high risk of depressed mood, defined as elevated level of depressive symptoms. This study describes baseline socio-demographic, cognitive, psychosocial, and health- and drug-related correlates of depressed mood in 267 stimulant-using homeless G/B young men who entered a study designed to reduce […]

Co-occurring risk behaviors among White, Black, and Hispanic US high school adolescents with suicide attempts requiring medical attention, 1999-2007: implications for future prevention initiatives.


Depression and alcohol dependence: one syndrome or two? A comparison of disability, suicidal risk and coping styles.

Depression and Alcoholism are common disabling conditions and are associated with high suicidal risk. The present study was conducted at Vidya Sagar Department of Psychiatry, PGIMS, Rohtak (Haryana). Patients, each of severe depression (n = 30) and alcohol dependence (n = 30) as per ICD-10 were evaluated on Disability Assessment Schedule, Suicide Risk Estimator Scale, […]

Suicides in older adults: a case-control psychological autopsy study in Australia.


Frequency and clinical features of suicide attempts in elderly patients in Japan.