Real‑world depression, anxiety and safety outcomes of intramuscular ketamine treatment: A retrospective descriptive cohort study

Background: Ketamine has emerged as a promising pharmacotherapy for depression and other mental illnesses, and the intramuscular (IM) administration of ketamine is now offered at many North American outpatient psychiatric clinics. However, a characterization of the outpatient population receiving IM ketamine treatment and an evaluation of the real-world depression, anxiety, and safety outcomes of long-term psychiatric […]

Parenthood and lower risk of suicide in women and men: The total Swedish population followed across adulthood

Background Previous studies suggest a protective effect of parenthood on suicide, but little is known about how the association may change across the lifespan, or in relation to sex, marital status or occurrence of psychiatric disorders. Methods We followed a cohort of over 5 million Swedish women and men, from 1991 to 2011, up to […]

Workplace bullying and risk of suicide and suicide attempts: A register-based prospective cohort study of 98 330 participants in Denmark

Objectives: The aim of this study was to analyze whether individuals reporting exposure to workplace bullying had a higher risk of suicidal behavior, including both suicide attempt and death by suicide, than those not reporting such exposure. Methods: Using a prospective cohort study design, we linked data from nine Danish questionnaire-based surveys (2004–2014) to national […]

Suicides in Aboriginal and non-Aboriginal people following hospital admission for suicidal ideation and self-harm: A retrospective cohort data linkage study from the Northern Territory

Purpose: This study aimed to explore risk factors for suicide in Aboriginal and non-Aboriginal people following hospital admission for suicidal ideation and self-harm in the Northern Territory, Australia to help clarify opportunities for improved care and intervention for these population groups. Methods: Individuals with at least one hospital admission involving suicidal ideation and/or self-harm between 1 July […]

Mental disorders and suicide risk among cancer patients: A nationwide cohort study

Although cancer patients are known to experience mental disorders and face suicide risk, little is known about the relationship between mental illness and death by suicide in this group. As such, this study aims to examine the association between mental disorders and suicide risk among cancer patients. We used nationally representative cohort data, and included […]

Predictors of suicidal ideation, suicide attempt and suicide death among people with major depressive disorder: A systematic review and meta-analysis of cohort studies

This meta-analysis examined the predictors of suicide-related behaviors by three different outcomes which was suicidal ideation, suicide attempts and suicide death. Twenty-nine predictors (ten for suicidal ideation, thirteen for suicide attempts and six for suicide death) from 24 cohort studies covering 954,822 participants with major depressive disorders were identified in this study. Previous suicidal behaviors were […]

Using natural language processing to extract self-harm and suicidality data from a clinical sample of patients with eating disorders: A retrospective cohort study

Objectives: The objective of this study was to determine risk factors for those diagnosed with eating disorders who report self-harm and suicidality. Design and setting: This study was a retrospective cohort study within a secondary mental health service, South London and Maudsley National Health Service Trust. Participants: All diagnosed with an F50 diagnosis of eating disorder from January […]

Suicide and psychosis: Results from a population-based cohort of suicide death (N=4380)

Approximately 5% of individuals with schizophrenia die from suicide. However, suicide in psychosis is still poorly characterized, partly due to a lack of adequate population-based clinical or genetic data on suicide death. The Utah Suicide Genetics Research Study (USGRS) provides a large population-based cohort of suicide deaths with medical record and genome-wide data (N = 4380). […]

Prediction of recurrent suicidal behavior among suicide attempters with Cox regression and machine learning: A 10-year prospective cohort study

Background Research on predictors and risk of recurrence after suicide attempt from China is lacking. This study aims to identify risk factors and develop prediction models for recurrent suicidal behavior among suicide attempters using Cox proportional hazard (CPH) and machine learning methods. Methods The prospective cohort study included 1103 suicide attempters with a maximum follow-up of 10 years from […]

Effects of the COVID-19 pandemic on primary care-recorded mental illness and self-harm episodes in the UK: A population-based cohort study

Background The COVID-19 pandemic has adversely affected population mental health. We aimed to assess temporal trends in primary care-recorded common mental illness, episodes of self-harm, psychotropic medication prescribing, and general practitioner (GP) referrals to mental health services during the COVID-19 emergency in the UK. Methods We did a population-based cohort study using primary care electronic […]

National cross-sectional cohort study of the relationship between quality of mental healthcare and death by suicide

Background Patient safety-based interventions aimed at lethal means restriction are effective at reducing death by suicide in inpatient mental health settings but are more challenging in the outpatient arena. As an alternative approach, we examined the association between quality of mental healthcare and suicide in a national healthcare system. Methods We calculated regional suicide rates for Department […]

Suicide and self-harm in adult survivors of critical illness: Population based cohort study

Objective To analyse the association between survival from critical illness and suicide or self-harm after hospital discharge. Design Population based cohort study using linked and validated provincial databases. Setting Ontario, Canada between January 2009 and December 2017 (inclusive). Participants Consecutive adult intensive care unit (ICU) survivors (≥18 years) were included. Linked administrative databases were used to compare ICU hospital […]

Racial/ethnic, sex, sexual orientation, and socioeconomic disparities in suicidal trajectories and mental health treatment among adolescents transitioning to young adulthood in the USA: A population-based cohort study

Suicide is the second leading cause of death for people aged 10-34 years old. Limited research has documented extant heterogeneities in suicide across the life course and among diverse sociodemographic groups. There is also limited research on the influences of mental health utilization on suicidal trajectories across the life course. This study aims to: (1) […]

The effect of income level on all-cause mortality and suicide among patients using antidepressants: A population-based cohort study

Background: To investigate whether household income levels are associated with all-cause mortality and suicide in patients using antidepressant agents. Methods: We analyzed data from 75,782 patients using antidepressants, acquired from the Korean National Health Insurance claims database (2002-2013). Each patient was monitored until December 2013 or until death, whichever occurred sooner. Cox proportional hazard models were used […]

Work related sexual harassment and risk of suicide and suicide attempts: Prospective cohort study

Objective To analyse the relation between exposure to workplace sexual harassment and suicide, as well as suicide attempts. Design Prospective cohort study. Setting Sweden. Participants 86 451 men and women of working age in paid work across different occupations responded to a self-report questionnaire including exposure to work related sexual harassment between 1995 and 2013. The analytical sample included 85 205 […]

Sex-dependent associations of low birth weight and suicidal ideation in childhood: A community-based cohort study.

Low birth weight (LBW; < 2,500 g) has been identified as a risk factor for adverse mental health outcomes over the life span. However, little is known about the association of LBW and suicidal ideation in middle and late adulthood. We investigated N = 8,278 participants of a representative community cohort: 3,849 men (46.5%) and 4,429 women (53.5%) (35–74 years of age). […]

Poor psychological health and 5-year suicide mortality: A population-based prospective cohort study

Objective The objective was to investigate associations between the General Health Questionnaire with twelve sub-items (GHQ-12) and prospective five-year suicide mortality. The two commonly used GHQ-12 cut-offs (2/3 and 3/4) were analyzed. Method The 2008 public health survey, which was conducted in the autumn of 2008 in Scania, southern Sweden, is based on a postal […]

Incidence, clinical management, mortality risk following self harm among children and adolescents: Cohort study in primary care

Objectives To examine temporal trends in sex and age specific incidence of self harm in children and adolescents, clinical management patterns, and risk of cause specific mortality following an index self harm episode at a young age. Main outcome measures In the first phase, temporal trends in sex and age specific annual incidence were examined. In the […]

Age, period, and cohort trends in mood disorder indicators and suicide-related outcomes in a nationally representative dataset, 2005-2017

Drawing from the National Survey on Drug Use and Health (NSDUH; N = 611,880), a nationally representative survey of U.S. adolescents and adults, we assess age, period, and cohort trends in mood disorders and suicide-related outcomes since the mid-2000s. Rates of major depressive episode in the last year increased 52% 2005–2017 (from 8.7% to 13.2%) […]

Suicide and all-cause mortality in Swedish deployed military veterans: A population-based matched cohort study.

Objective To investigate suicide and mortality risk in deployed military veterans versus non-deployed comparators who had gone through military conscription testing. Design Population-based matched cohort study. Setting Sweden. Participants Participants were identified from the Military Service Conscription Register and deployment status from the Swedish Military Information Personnel Register. Of 1.9million conscripts, 21 721 had deployed […]

Suicide and self-harm trends in recent immigrant youth in Ontario, 1996-2012: A population-based longitudinal study.

Objective To describe the trends in suicide and emergency department (ED) visits for self-harm in youth by immigration status and immigrant characteristics. Design Population-based longitudinal cohort study from 1996 to 2012 using linked health and administrative datasets. Setting Ontario, Canada. Participants Youth 10 to 24 years, living in Ontario, Canada. Exposure The main exposure was immigrant status (recent immigrant (RI) versus […]

Suicides by persons reported as missing prior to death: A retrospective cohort study.

Suicides by missing persons show several distinct characteristics in comparisons to other suicides. The findings have implications for development of suicide prevention strategies focusing on early identification and interventions targeting this group. In particular, it may offer assistance to police in designing risk assessment procedures and subsequent investigations of missing persons.

Criminality and suicide: A longitudinal Swedish cohort study.