Resource Tag: CHOLESTEROL

Suicide and suicidal tendencies have become a global public health problem. It is reported that more than 700 000 deaths are due to suicide. Suicide is the fourth leading cause of death among 15-29 year olds. Therefore, there are many studies conducted to find suitable solutions to prevent or reduce suicidal deaths. Many epidemiological surveys […]

Background: Mood disorders are associated with a high risk of suicide. Statin therapy has been implicated in this relationship. Aims: To further clarify reported associations between suicide and cholesterol in mental health conditions, we conducted an analysis of dietary, clinical, and suicidal ideation measures in community-living adults with mood disorders. Method: Data were used from a cross-sectional study […]

Background Cholesterol and cholesterol metabolism, involved in continued neural plasticity, has been associated to suicide and suicidal behavior. Apolipoprotein E (ApoE) plays an important role in the cholesterol metabolism. The purpose of this study was to investigate whether ApoE in cerebrospinal fluid was related to severity of suicidal behavior as measured by number of earlier […]

There are inconsistent reports showing that the relationship between total cholesterol (TC) level and suicidality might be gender-specific. We compared 30 first-episode schizophrenia (FES) patients reporting suicidal ideation based on the Operational Criteria for Psychotic Illness (OPCRIT) checklist with 70 FES patients, who have never experienced suicidal ideation. After controlling for potential confounders, higher TC […]

~

This review considers the evidence from epidemiological studies on serum cholesterol lowering & psychiatric disturbances. The available evidence does not seem to substantiate the view that large-scale intervention to reduce cholesterol concentrations could lead to more violent & aggressive behaviour, & generally greater unhappiness. In recent trials using statin treatment, there were slightly fewer deaths […]

This article examines the relationship between low serum cholesterol & mood disorders as well as the relationship between cholesterol & suicide ideation, suicide attempts, & parasuicide. (60 refs.)

This article reviews molecular genetic studies in suicidal behaviour & emphasizes findings on new genes. Topics reviewed include: serotonin & suicidal behaviour; genes involved in serotonergic neurotransmission; catecholamines; genes involved in neurotransmission; neurotrophins; & other genes & suicidal behaviour. (167 refs.)

~

~

~

The authors examined the relationship between cholesterol metabolism & suicidality in carriers of Smith-Lemli-Opitz syndrome & their families. Structured interviews were conducted with 51 carriers of this syndrome & 54 matched comparison subjects. There were significantly more suicide attempters & completers among the biological relatives of Smith-Lemli-Opitz syndrome carriers than comparison subjects but family history […]

Published in “The Suicidal Process: Challenges for Treatment and Prevention”

~

In order to study the association between serum total cholesterol, depression & suicide, a total of 29,133 men aged 50-69 years were followed up for 5-8 years. Serum protein & high-density lipoprotein cholesterol concentrations were analysed, as were levels of depression, treatment for depression, & deaths from suicide. The researchers found that low serum total […]

~

In this investigation, the course of serum cholesterol concentrations was measured in depressed patients during treatment. Degrees of depression & suicidality were measured with the Hamilton Depression Rating Scale. Although there was a significant reduction in depression & suicidality scores, neither a significant changed in serum cholesterol levels nor a correlation between cholesterol levels & […]

The aim of the current study was to determine which variable would be a better predictor of suicide risk: perceived social support or serum cholesterol level. Perceived social support was found to be a better predictor for African Americans. Depressed patients with a history of suicide attempt had a significantly lower serum cholesterol level, scored […]

For the original article by D Lester, please see SIEC #2003-1311

This study investigated the associations between total serum cholesteral levels, violent & suicidal behavior, age of onset of the conduct disorder, & the age of death among 250 Finnish male criminal offenders with antisocial personality disorders. No associations were found between total serum cholesteral levels & a history of suicide attempts & slashing. Low total […]