CSF apolipoprotein E in attempted suicide

Cholesterol and cholesterol metabolism, involved in continued neural plasticity, has been associated to suicide and suicidal behavior. Apolipoprotein E (ApoE) plays an important role in the cholesterol metabolism. The purpose of this study was to investigate whether ApoE in cerebrospinal fluid was related to severity of suicidal behavior as measured by number of[…]

Higher total cholesterol level is associated with suicidal ideation in first-episode schizophrenia females.

There are inconsistent reports showing that the relationship between total cholesterol (TC) level and suicidality might be gender-specific. We compared 30 first-episode schizophrenia (FES) patients reporting suicidal ideation based on the Operational Criteria for Psychotic Illness (OPCRIT) checklist with 70 FES patients, who have never experienced suicidal ideation. After controlling for potential confounders, higher TC[…]

Association between serum cholesterol and depression, aggression and suicidal ideation in war veterans with posttraumatic stress disorder: A cross-sectional study.


The Association of low Serum Cholesterol With Depression and Suicidal Behaviours: new Hypotheses for the Missing Link

This review considers the evidence from epidemiological studies on serum cholesterol lowering & psychiatric disturbances. The available evidence does not seem to substantiate the view that large-scale intervention to reduce cholesterol concentrations could lead to more violent & aggressive behaviour, & generally greater unhappiness. In recent trials using statin treatment, there were slightly fewer deaths[…]

Cholesterol Quandaries: Relationship to Depression and the Suicidal Experience

This article examines the relationship between low serum cholesterol & mood disorders as well as the relationship between cholesterol & suicide ideation, suicide attempts, & parasuicide. (60 refs.)

Molecular Genetic Findings in Suicidal Behavior: What is Beyond the Serotonergic System?

This article reviews molecular genetic studies in suicidal behaviour & emphasizes findings on new genes. Topics reviewed include: serotonin & suicidal behaviour; genes involved in serotonergic neurotransmission; catecholamines; genes involved in neurotransmission; neurotrophins; & other genes & suicidal behaviour. (167 refs.)

Serum Cholesterol and Leptin Levels in Patients With Borderline Personality Disorder


Clinical Assessment of Suicide Risk in Depressive Disorder


Cholesterol Metabolism and Suicidality in Smith-Lemli-Opitz Syndrome Carriers

The authors examined the relationship between cholesterol metabolism & suicidality in carriers of Smith-Lemli-Opitz syndrome & their families. Structured interviews were conducted with 51 carriers of this syndrome & 54 matched comparison subjects. There were significantly more suicide attempters & completers among the biological relatives of Smith-Lemli-Opitz syndrome carriers than comparison subjects but family history[…]

High Cholesterol, Triglycerides, and Body-mass Index in Suicide Attempters