The mediating role of reflective functioning in the association between childhood trauma and suicide attempt

Background Childhood trauma is intimately related with suicidal behaviour. Patients who have suffered childhood trauma develop impaired Reflective Functioning (RF), which refers to the capacity to understand ourselves and others in terms of intentional mental states. An improvement in RF has been associated with a reduction in suicidal attempts, but the mediating role of RF between […]

The effects of childhood trauma on stress-related vulnerability factors and indicators of suicide risk: An ecological momentary assessment study

Background: Childhood trauma is experienced by approximately one third of young people in the United Kingdom and has been shown to confer an increased risk for mental health difficulties in adulthood. Understanding the associations between these factors before negative health outcomes manifest in adulthood is imperative to help inform the development of interventions. The aims of […]

Wakȟáŋyeža (Little Holy One) – an intergenerational intervention for Native American parents and children: A protocol for a randomized controlled trial with embedded single-case experimental design

Background Trauma within Native American communities compromises parents’ parenting capacity; thus, increasing childrens’ risk for substance use and suicide over the lifespan. The objective of this manuscript is to describe the Wakȟáŋyeža (Little Holy One) intervention and evaluation protocol, that is designed to break cycles of intergenerational trauma, suicide, and substance use among Fort Peck […]

Associations between early child adversity and lifetime suicide attempts among gender diverse individuals: A moderated mediation

Background This study examines the effect of adverse childhood experiences (ACEs) on lifetime suicide attempts (LSA) across five gender subgroups (i.e., transgender men, transgender women, transgender non-binary, cisgender men and cisgender women). Objective To examine (1) the prevalence of LSA across gender identity subgroups; (2) whether the association between ACEs and LSA is moderated by […]

Suicidality among Syrian refugee children in Jordan

History of adverse events in childhood is one of the strongest predictors of developing negative mental health outcomes with suicidality being the most devastating consequence. Syrian refugee children are at very high risk of developing mental illness, however, the prevalence and significance of suicidal thoughts among this population remains undocumented. A total of 339 Syrian […]

Wakȟáŋyeža (Little Holy One): An intergenerational intervention for Native American parents and children: a protocol for a randomized controlled trial with embedded single-case experimental design

Background Trauma within Native American communities compromises parents’ parenting capacity; thus, increasing childrens’ risk for substance use and suicide over the lifespan. The objective of this manuscript is to describe the Wakȟáŋyeža (Little Holy One) intervention and evaluation protocol, that is designed to break cycles of intergenerational trauma, suicide, and substance use among Fort Peck […]

Brief report: The association of adverse childhood experiences and suicide-related behaviors among 10th-grade secondary school students

The association between adverse childhood experiences and suicide-related behaviors (SRB) of adolescents has been widely studied in Western high-income countries, but not yet in Latin America. The aim of this study was to determine this association and to explore a dose-response relationship between adverse childhood experiences and SRB in Chile. We conducted a cross-sectional survey […]

The relationship between mental pain, suicide risk, and childhood traumatic experiences: Results from a multicenter study

Objective: Mental pain and exposure to maltreatment are significant risk factors for suicidal behavior. This study aimed to investigate whether mental pain could be associated with a recent suicide attempt and whether it could mediate the relationship between childhood traumatic experiences and suicide risk in psychiatric patients. Methods: A multicenter observational study was organized as a joint […]

The prevalence and association of adverse childhood experiences with suicide risk behaviors among adolescents and youth in Zimbabwe

Suicide poses a significant public health concern, particularly among adolescents and youth exposed to adverse childhood experiences (ACEs). However, little research exists on understanding ACEs’ prevalence and suicidality consequences in Zimbabwe. Therefore, this study examined the prevalence and association between individual and cumulative ACEs with suicide risk among adolescents and youth in Zimbabwe. The study […]

Embers of the past: Early childhood traumas interact with variation in the P2RX7 gene implicated in neuroinflammation on markers of current suicide risk

Both early childhood traumatic experiences and current stress increase the risk of suicidal behaviour, in which immune activation might play a role. Previous research suggests an association between mood disorders and P2RX7 gene encoding P2X7 receptors, which stimulate neuroinflammation. We investigated the effect of P2RX7 variation in interaction with early childhood adversities and traumas and recent stressors on lifetime […]

Maladaptive behaviours of maternal orphans in high schools of Tshwane North of Gauteng, South Africa

Background Some orphaned adolescents find it difficult to cope and adjust to the loss of a mother. Studies to explore specific adjustment challenges experienced by this vulnerable group, are necessitated by the growing need to inform support services for orphans. Aim This study sought to explore maladaptive behaviours among adolescent maternal orphans. Setting Participants were […]

The moderated mediating effect of community integration in depressive symptoms which are related to childhood adversity and suicide attempts by adolescents who have dropped out of school

The aim of this study was to verify the moderated mediating effect of community integration on the influence of childhood adversity on suicide attempts in adolescent who have dropped out of school and examine the mediating effect of depressive symptoms. This study used the data of the first year from a Longitudinal Survey and Support […]

Prospective longitudinal associations between adverse childhood experiences and adult mental health outcomes: A protocol for a systematic review and meta‑analysis

Background Research cites a strong, dose–response relationship between adverse childhood experiences (ACEs) and poor adult mental health outcomes including anxiety, depression, post-traumatic stress disorder (PTSD), self-harm, suicidality, and psychotic-like experiences. Aim To systematically investigate the existence and strength of association between ACEs and adult mental health outcomes in prospective longitudinal studies. The review will focus […]

Mood disorders and aggressive traits mediate effects of reported childhood adversity on suicide attempt risk

Background Childhood adversity (CA) is linked to suicidal behavior as well as to mood disorders and aggressive traits. This raises the possibility that depression and aggressive traits mediate the relationship of childhood adversity to suicide risk. Moreover, it is not known if they operate independently or interactively. Aims To determine whether, and how, mood disorders […]

Association of childhood adversities with psychosocial difficulties among Chinese children and adolescents

Background: Adverse childhood experiences (ACEs) have been well recognized as risk factors for various adverse outcomes. However, the impacts of ACEs on psychological wellbeing among Chinese children and adolescents are unknown. Methods: In total, 27 414 participants (6592 Grade 4–6 and 20 822 Grade 7–12 students) were included and information on ACEs and various psychosocial […]

Childhood trauma and suicide: Associations between impulsivity, executive functioning, and stress

Background: Suicide is a leading cause of death worldwide, and childhood trauma has been found to be an important risk factor. However, the mechanisms linking trauma to suicide risk remain unclear. Aims: The current registered report sought to (1) investigate whether childhood trauma and its subtypes were related to suicide risk in adulthood and (2) […]

Suicidal attempt in adolescents with major depressive disorder

Aim: In this study, we aimed to assess the sociodemographic and clinical characteristics of adolescents diagnosed with major depressive disorder (MDD), with and without suicide attempts, as well as to investigate the factors predicting suicide attempts. Materials and Methods: This study included 151 adolescents aged between 12 and 18 years, who were diagnosed with MDD […]

The relationship between adverse childhood experiences and suicide-related behaviours in Indigenous clients seeking substance use treatment

Indigenous populations in Canada are at higher risk of adverse childhood experiences (ACEs; e.g., abuse, neglect, or other household challenges before the age of 18) when compared to non-Indigenous populations. As the number of ACEs increase, so do rates of substance use and suicide risk. In non-Indigenous populations, the presence of prior suicide-related behaviours (SRBs) […]

The devastating clinical consequences of child abuse and neglect: Increased disease vulnerability and poor treatment response in mood disorders

A large body of evidence has demonstrated that exposure to childhood maltreatment at any stage of development can have long-lasting consequences. It is associated with a marked increase in risk for psychiatric and medical disorders. This review summarizes the literature investigating the effects of childhood maltreatment on disease vulnerability for mood disorders, specifically summarizing cross-sectional […]

Life adversities of clients seeking advice for suicidal ideation from an online peer counseling service: Characteristics and associations with outcomes

Objective: Germany is a low-threshold, anonymous and free-of-charge online suicide prevention service for people up to 25 years of age. Its special feature is that counseling is provided by trained and continuously supervised voluntary peers. This study addresses the following research questions: (1) Which life adversities are reported by the clients of [U25]? (2) Are […]

Adverse childhood experiences and clustering of high-risk behaviors among high school students: A cross-sectional study

Objectives: This study assessed the association between adverse childhood experiences (ACEs) and clustering of high-risk behaviors in a sample of high school students. Study design: This was a cross-sectional study. Methods: A sample of students who attended randomly selected classes in 99 high schools completed the 2019 Nevada Youth Risk Behavior Survey (N = 4959). The survey included […]

Predicting prolonged non-suicidal self-injury behaviour and suicidal ideations in adolescence: The role of personal and environmental factors

Suicide is one of the leading causes of death among adolescents and repetitional suicidal ideations (SI) and non-suicidal self-injury (NSSI) often precede it. In order to improve recognition of youth who are at high risk of suicide, current study aims to identify which individual variables (personality, self-concept and adverse childhood experiences – ACE) predict prolonged […]

Youth suicide and self-harm: Latent class profiles of adversity and the moderating roles of perceived support and sense of safety

Research suggests that exposure to adversity can lead to an increased risk of experiencing suicidal and self-injurious thoughts or behaviours, but few studies have examined whether different patterns of adversity are differentially associated with youth suicide/self-harm. The current study aims to explore the relationship between exposure to adversity across various social domains and youth self-harm […]