Understanding the causal relationships of attention-deficit/ hyperactivity disorder with mental disorders and suicide attempt: A network Mendelian randomisation study

Background: Attention-deficit/hyperactivity disorder (ADHD) is a lifespan neurodevelopmental condition resulting from complex interactions between genetic and environmental risk factors. There is evidence that ADHD is associated with other mental disorders, but it remains unclear whether and in what way a causal relationship exists. Objective: To investigate the direct and indirect causal paths between ADHD and seven common […]

Risk factors of suicidal spectrum behaviors in adults and adolescents with attention‑deficit / hyperactivity disorder: A systematic review

Introduction Adolescents and adults with attention-deficit/hyperactivity disorder (ADHD) are at increased risk of suicidal spectrum behaviors (SSBs). However, there is limited knowledge about risk factors triggering SSBs in this group of people. Objective To explore published literature concerning factors that may increase the risk of SSBs in adults and adolescents with ADHD. Methods A systematic […]

The importance of recognizing worthlessness for suicide prevention in adolescents with attention-deficit/hyperactivity disorder

Background: Attention-deficit/hyperactivity disorder (ADHD) is one of the most common psychiatric diagnoses among children and adolescents. Depression and general anxiety disorder (GAD) are often co-occurring with ADHD among children and adolescents. Previous studies have found that ADHD, depression and GAD are all strongly correlated with suicidal thoughts and planning. Aim: The current study aimed to further explore […]

Missed opportunities for suicide prevention in teens with ADHD

Background: Epidemiological evidence links Attention Deficit Hyperactivity Disorder (ADHD) to increased risk of suicide. The research aimed to describe awareness among primary care pediatricians (PCPs) of ADHD as a  risk factor for suicide and PCPs’ practices of suicide risk assessment (SRA) and firearms safety assessment (FSA) in teens with ADHD. Method: An online survey was […]

Effect of comorbid ADHD on mortality in women with borderline personality disorder

Background Many similarities exist between borderline personality disorder (BPD) and attention-deficit/hyperactivity disorder (ADHD), more so in women than in men. People with comorbid ADHD and BPD represent a subgroup of BPD patients with distinct symptom expression and, consequently, a different prognosis. We used Swedish national high quality registers to assess whether such comorbidity is related […]

Investigation of the interpersonal theory of suicide in the context of attention-deficit/hyperactivity disorder symptomatology and suicide ideation

Objective The current study examines components of the Interpersonal Theory of Suicide as mediators of the association between attention-deficit/hyperactivity disorder (ADHD) symptoms and suicide ideation in college students with elevated depressive symptoms. Specifically, indirect effects of perceived burdensomeness and thwarted belongingness were simultaneously evaluated on the association between self-reported ADHD symptoms and suicide ideation, controlling […]

Healthcare utilization and comorbidity shortly before suicide mortality in patients with attention‑deficit/hyperactivity disorder: A nested case–control study

Few studies have analyzed healthcare utilization before suicide among individuals with attention-deficit/hyperactivity disorder (ADHD). This study examined the pattern of healthcare utilization and comorbidities shortly before death among patients with ADHD who died by suicide and compared these data with those of living controls. This study used Taiwan’s National Health Insurance Research Database to identify […]

The dark side of ADHD: Factors associated with suicide attempts among those with ADHD in a national representative Canadian sample

Aim This study investigated the prevalence and odds of suicide attempts among adults with attention deficit hyperactivity disorder (ADHD) compared to those without and identified factors associated with suicide attempts among adults with ADHD. Methods Secondary analysis of the nationally representative Canadian Community Health Survey–Mental Health (CCHS-MH) (n = 21,744 adults, of whom 529 had ADHD). Respondents […]

Healthcare utilization and comorbidity shortly before suicide mortality in patients with attention‑deficit/hyperactivity disorder: A nested case–control study

Few studies have analyzed healthcare utilization before suicide among individuals with attention-deficit/hyperactivity disorder (ADHD). This study examined the pattern of healthcare utilization and comorbidities shortly before death among patients with ADHD who died by suicide and compared these data with those of living controls. This study used Taiwan’s National Health Insurance Research Database to identify […]

Evaluation of attention-deficit/hyperactivity disorder medications, externalizing symptoms, and suicidality in children

Importance  Childhood suicidality (ie, suicidal ideation or attempts) rates are increasing, and attention-deficit/hyperactivity disorder (ADHD) and externalizing symptoms are common risk factors associated with suicidality. More data are needed to describe associations of ADHD pharmacotherapy with childhood suicidality. Objective  To investigate the associations of ADHD pharmacotherapy with externalizing symptoms and childhood suicidality. Design, Setting, and Participants  In this […]

Increased risk of COVID-19 infection and mortality in people with mental disorders: Analysis from electronic health records in the United States

Concerns have been expressed that persons with a pre‐existing mental disorder may represent a population at increased risk for COVID‐19 infection and with a higher likelihood of adverse outcomes of the infection, but there is no systematic research evidence in this respect. This study assessed the impact of a recent (within past year) diagnosis of […]

A naturalistic study of youth referred to a tertiary care facility for acute hypomanic or manic episode

Background: Bipolar Disorders (BD) in youth are a heterogeneous condition with different phenomenology, patterns of comorbidity and outcomes. Our aim was to explore the effects of gender; age at onset (prepubertal- vs. adolescent-onset) of BD; and elements associated with attention deficit hyperactivity disorder (ADHD) and Substance Use Disorder (SUD) comorbidities, severe suicidal ideation or attempts, and […]

ADHD, financial distress, and suicide in adulthood: A population study

Attention-deficit/hyperactivity disorder (ADHD) exerts lifelong impairment, including difficulty sustaining employment, poor credit, and suicide risk. To date, however, studies have assessed selected samples, often via self-report. Using mental health data from the entire Swedish population (N = 11.55 million) and a random sample of credit data (N = 189,267), we provide the first study of objective financial […]

The association between attention deficit/hyperactivity disorder symptoms and the number of suicide attempts among male young adult with unipolar and bipolar depression

Objectives: Mood disorder is highly comorbid with attention deficit/hyperactivity disorder (ADHD), and comorbid ADHD symptoms are associated with suicide risk. The aim of this study was to examine the association between comorbid ADHD symptoms and the number of suicide attempts among patients with unipolar and bipolar depression. Methods: In this cross-sectional study, 100 patients with either unipolar […]

Association of ADHD symptoms, depression and suicidal behaviors with anxiety in Chinese medical college students

Background Anxiety is one of the most common psychiatric disorder and imposes a great burden on both the individual and the society. Previous studies indicate a high comorbidity of anxiety disorders and Attention Deficit Hyperactivity Disorder (ADHD). However, few studies have examined the comorbidity of anxiety and ADHD among medical college students in mainland China. […]

Working memory mediates increased negative affect and suicidal ideation in childhood attention-deficit/hyperactivity disorder

Children with attention-deficit/hyperactivity disorder (ADHD) are at greater risk for suicidal ideation and suicide attempts compared to those without ADHD. Increased risk is at least partially attributable to a subset of children with ADHD and comorbid depression or disruptive behavior disorders; however, the early predictors and mechanisms driving increased risk are not well understood. Here, […]

Stress accounts for the association between ADHD symptoms and suicide ideation when stress-reactive rumination is high.

ADHD symptoms are significantly associated with suicide ideation. However, the variables that explain this association remain unknown. This study tested a theoretical model in which stress was hypothesized to account for the association between ADHD symptoms and suicide ideation among individuals high, but not low, in ruminative responding to stress. We examined this model in […]

Comorbidity of adult attention deficit and hyperactivity disorder in bipolar and unipolar patients.

Introduction: The co-occurrence of attention deficit hyperactivity disorder (ADHD) in affective disorder patients is considerably high. The aims of the present study were to search for the frequency and impact of ADHD co-occurrence on the clinical features of affective disorders and to examine the relationship between the dominant affective temperaments and ADHD. Methods: In total, […]

Self-injury and externalizing pathology: A systematic literature review.

Background During the last decade there is a growing scientific interest in nonsuicidal self-injury (NSSI). The aim of the current paper was to review systematically the literature with a special focus on the associations between self-injurious behaviours and externalizing psychopathology. An additional aim was to review terminology and measurements of self-injurious behaviour and the connection […]

Comorbidity of adult attention deficit and hyperactivity disorder in bipolar and unipolar patients.

Introduction: The co-occurrence of attention deficit hyperactivity disorder (ADHD) in affective disorder patients is considerably high. The aims of the present study were to search for the frequency and impact of ADHD co-occurrence on the clinical features of affective disorders and to examine the relationship between the dominant affective temperaments and ADHD. Methods: In total, […]

Lucky horseshoes: A tale from the Iris the Dragon Series.

In “Lucky Horseshoes” a young girl named Skippy finds it very hard to concentrate at school. Loud sounds and even lights are distracting. She finds that daydreaming or getting up and moving helps her control the distractions – but doing that disrupts the class. Skippy meets Iris the Dragon and, with the help of her […]

Early-adult correlates of maltreatment in girls with attention-deficit/hyperactivity disorder: Increased risk for internalizing symptoms and suicidality.

We examined whether maltreatment experienced in childhood and/or adolescence prospectively predicts young adult functioning in a diverse and well-characterized sample of females with childhood-diagnosed attention-deficit/hyperactivity disorder (N = 140). Participants were part of a longitudinal study and carefully evaluated in childhood, adolescence, and young adulthood (Mage = 9.6, 14.3, and 19.7 years, respectively), with high […]

Very early predictors of adolescent depression and suicide attempts in children with attention-deficit/hyperactivity disorder.

All subtypes of ADHD in young children robustly predict adolescent depression and/or suicide attempts 5 to 13 years later. Furthermore, female sex, maternal depression, and concurrent symptoms at 4 to 6 years of age predict which children with ADHD are at greatest risk for these adverse outcomes. Identifying high-risk young children with ADHD sets the […]