Long term effect of reduced pack sizes of paracetamol on poisoning deaths and livertransplant activity in England and Wales: Interrupted time series analyses

Objective: To assess the long term effect of United Kingdom legislation introduced in September 1998 to restrict pack sizes of paracetamol on deaths from paracetamol poisoning and liver unit activity. Design: Interrupted time series analyses to assess mean quarterly changes from October 1998 to the end of 2009 relative to projected deaths without the legislation based on […]

Trends of intentional drug overdose among youth: A population-based cohort study

Background: Intentional overdose is the commonest form of self-harm in adolescents globally. We explored temporal trends in intentional overdose among youth. Methods: Using multiple linked healthcare databases, we conducted a population-based cohort study in Ontario, Canada, from 2002 to 2015. We included all patients aged 8 to 19 years who presented to an emergency department (ED) or were […]

Over-the-counter drugs and other substances used in attempted suicide presented to emergency departments in Montreal, Canada: A cross sectional study

Background: Over-the-counter (OTC) analgesics are frequently used in suicide attempts. Accessibility, toxicity, and unsupervised acquisition of large amounts may be facilitators. Aims: To identify patient characteristics associated with OTC drug use as a suicide attempt method among adults. Method: A cross-sectional study was conducted using chart review of all individuals who presented to the emergency […]

Childhood suicide attempts with acetaminophen in Denmark: characteristics, social behaviour, trends and risk factors.